Push dose epinephrine is prepared as 1 mL of a solution with what concentration?

Push dose epinephrine is prepared as 1 mL of a solution with what concentration?

• A. 1:1,000
• B. 1:10,000
• C. 1:100,000
• D. 1:50,000

Answer: (C)

Push-dose epinephrine is meant to deliver a small, easily titratable amount, about 10 micrograms per dose. To hit that amount with a 1 mL syringe, the solution in that 1 mL must contain 10 µg of epinephrine. That corresponds to a concentration of 1:100,000, which is 0.01 mg per mL (10 µg per mL). If you used a more concentrated mix, you’d deliver far more than 10 µg per dose, increasing the risk of hypertension or tachycardia; if you used a more dilute mix, you’d risk under-dosing. So 1 mL of a 1:100,000 solution provides the intended 10 µg per push, matching typical push-dose practice.

Push-dose epinephrine is meant to deliver a small, easily titratable amount, about 10 micrograms per dose. To hit that amount with a 1 mL syringe, the solution in that 1 mL must contain 10 µg of epinephrine. That corresponds to a concentration of 1:100,000, which is 0.01 mg per mL (10 µg per mL). If you used a more concentrated mix, you’d deliver far more than 10 µg per dose, increasing the risk of hypertension or tachycardia; if you used a more dilute mix, you’d risk under-dosing. So 1 mL of a 1:100,000 solution provides the intended 10 µg per push, matching typical push-dose practice.